Manchester City booked their place in the Champions League quarter-finals, but lost a home game for the first time since 2016 as they were beaten by Basel in the second leg of their last-16 tie.
City's 4-0 away win meant the second leg was a formality, with Pep Guardiola resting several first-team players.
Gabriel Jesus opened the scoring by tapping home Bernardo Silva's cross.
But Mohamed Elyounoussi lashed home a leveller and then set up Michael Lang's second-leg winner.
It is only the second time City have reached the quarter-finals of the European Cup or Champions League. Juventus, Real Madrid and Liverpool are the other sides to have clinched their last-eight spots this week.